The treatment strategies of stage IV colorectal cancer
synchronous CRLM (detected at time of diagnosis) is increasing compared with metachronous ( detected in the following 5 years after surgery (35%)) , probably due to improved imaging techniques leading to earlier diagnosis. Synchronous CRLM have less favourable cancer biology and expected survival than metachronous metastases as corroborated by their temporal presentation, but some studies showed no significant difference [7,8 ]. In CRC staging, the tumour is first scored with respect
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